Key Ingredients Found in Heart Health™ Advanced CoQ10:
Coenzyme Q10 (CoQSol-CF™) 102 mg
Coenzyme Q10 belongs to a family of substances called ubiquinones and is a water-insoluble, wax-like substance that is part of the respiratory chain. Since it is a coenzyme, it is necessary to support the action of an enzyme, and it has a similar structure to vitamin K. CoQ10 is found in each of the 50-75 trillion cells throughout the body, except for mature red blood cells. It has a multitude of health benefits at the cellular level, in the cardiovascular system, and with the body’s metabolism. It serves to revitalize and energize the body’s cells and immune system and contributes to increases in stamina and endurance by fueling the body’s energy production (ATP) cycle. It is beneficial to the cardiovascular system because it helps to protect the heart, maintain normal blood pressure, and promotes mental alertness and brain activity.*
The mechanism of action of supplemental coenzyme Q10 has yet to be clarified and is a matter of much speculation. However, much is known about the biochemistry of CoQ10. Coenzyme Q10 is a two-part compound that is composed of a long, fat-soluble isoprenoid tail that anchors the molecule in the inner membrane of the mitochondria; and quinine that is capable of accepting and transferring electrons through a portion of the respiratory chain. The “Q” stands for quinine and the “10” stands for the number of isoprenoid units in the tail portion of the molecule. It is synthesized in the cells and is involved in electron transport and energy production in mitochondria. In the cellular system, it functions to generate energy from oxygen, in the form of ATP, for bodily processes. It serves as a free radical scavenger and an antioxidant. The antioxidant activity in the mitochondria and cell membranes promote the stability and health of lipid membranes. Combining CoQ10 with vitamin E generates a synergistic antioxidant effect on lipoprotein and spares the vitamin E.*
Coenzyme Q10 can be found in spinach, broccoli, nuts, soy, organ and muscle meats, and fish. In 1977, a Japanese company succeeded in synthesizing coenzyme Q10, which made the nutrient available to the world. CoQ10 is absorbed in the small intestine and a steady-state concentration can be attained in the body in five to six weeks. In the body, it is found in the highest concentration in the cells of the heart, liver, kidney and pancreas. The liver produces small amounts of CoQ10, and then it is distributed to the rest of the body.
Vitamin E (d-alpha-Tocopherol): 200 IU
The most valuable sources of dietary vitamin E include vegetable oils, margarine, nuts, seeds, avocados and wheat germ. Safflower oil contains large amounts of vitamin E (about two thirds of the RDA in ¼ cup), and there are trace amounts in corn oil and soybean oil. Vitamin E is actually a family of related compounds called tocopherols and tocotrienols. Vitamin E is available in a natural or synthetic form. In most cases, the natural and synthetic forms are identical except the natural form of vitamin E is better absorbed and retained in the body. The natural form of alpha-tocopherol is known as “d-alpha tocopherol.” The synthetic “dl-” form is the most common form found in dietary supplements. For those individuals watching their dietary fat consumption, which is relatively common in the world of dieting, vitamin E intake is likely to be low, due to a reduced intake of foods with high fat content.*
The main health benefit of supplemental vitamin E comes from its immune-boosting antioxidant activity. It also promotes the normal healing of wounds and is known to promote cardiovascular health. Vitamin E is one of the most powerful fat-soluble antioxidants in the body. Vitamin E protects cell membranes from free radical damage.